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Neurological damage associated with HSV2


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6 hours ago, hopeing said:

I sometimes get a blocked inner ear, never used to get it before, can't say for sure but I wouldn't be surprised if its a side effect of the virus being in the ganglion near the ear. 

I don't think my hearing is actually damaged, just the fluid on the ear makes the hearing bad while its there. I also get hayfever so it may just be related to that, flushing my sinus with salt water spray tends to help.

Yes, there definitely seems to be a link, as when my hearing is worst I often have a lesion somewhere, but it's odd that it took nearly 30 years to have any effect on my ear. I've wondered if it has found it's way INTO the inner ear, rather than just near it. 

 

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On 5/20/2020 at 4:36 AM, Neuro_loss said:

Hi, thanks - I'd be surprised if I was deficient in any vitamins tbh because my diet is pretty good, and I eat quite a lot of B12-rich foods. That said, if I remove all nuts I'll probably have to take some supplements to counter what is lost. I eat turkey once a year at Christmas :-) Removing sugar and alcohol is going to be a struggle though.....

I haven't forgotten my own name yet, but I've forgotten a lot of other people's names!

 

 

I have pernicious anemia. My body can not absorb the B12 from food. So I have to take shots. It runs through welsh bloodlines really bad too. I’m like heins 57 and have so many different backgrounds. Lol. But my grandfathers parents are welsh. 

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On 5/17/2020 at 8:09 AM, WilsoInAus said:

the virus does not move ganglions from inside the body. The virus enters an infection site through the skin and infections the relevant ganglion. Sometimes people are infected at the same or similar time with the same type in two locations, however the virus has penetrated in the two locations. Note that the base of the spine is a branch of the genital ganglion.

I may be misunderstanding these studies, but reading these it seem that herpes can spread pretty widely within the nervous system.

"Examination of HSV-2 latency using polymerase chain reaction (PCR) techniques have demonstrated HSV-2 latency in ganglia throughout the central nervous system (CNS) axis, albeit at significantly lower frequencies than in the sacral ganglia. Latency of HSV-2 has also been demonstrated to occur in trigeminal ganglia. The widespread latency of HSV-2 suggests that the virus may reach ganglia far removed from the site of primary infection." https://jamanetwork.com/journals/jamaneurology/fullarticle/795486

"Herpes simplex virus (HSV) DNA was detected in 42% of all [cranial] ganglia surveyed" https://pubmed.ncbi.nlm.nih.gov/11718247

"The presence of HSV-1 and VZV genomes in both sensory and autonomic ganglia suggests that latency (and perhaps, reactivation) of these viruses extends beyond the trigeminal ganglion. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782560/

"HSV - 2 can spread not only to the dorsal root sensory ganglia (DRG), but to the autonomic parasympathetic neurons of the major pelvic ganglia (MPG) and the sympathetic chain" https://jvi.asm.org/content/jvi/early/2019/02/22/JVI.00227-19.full.pdf

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Elephant in the room?
On 5/21/2020 at 2:26 AM, Neuro_loss said:

Yes, there definitely seems to be a link, as when my hearing is worst I often have a lesion somewhere, but it's odd that it took nearly 30 years to have any effect on my ear. I've wondered if it has found it's way INTO the inner ear, rather than just near it. 

 

I was shown a good article about specific T cells produced in the gut that prevents migration of HSV through the body that could be insightful for those concerned or with rare complications like encephalitis. 

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Hey @inocula all those papers identify HSV-1 and HSV-2 in the trigeminal and sacral areas. Rarely were HSV-1 and HSV-2 found elsewhere and rarely in more than one ganglion. 

Please do not confuse the fact that VZV is known to be widespread and is of course not HSV-1/2.

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3 hours ago, Just a human being said:

I was shown a good article about specific T cells produced in the gut that prevents migration of HSV through the body that could be insightful for those concerned or with rare complications like encephalitis. 

Okay.....

Thanks, but any hint where this article might be found?

 

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3 hours ago, inocula said:

I may be misunderstanding these studies, but reading these it seem that herpes can spread pretty widely within the nervous system.

"Examination of HSV-2 latency using polymerase chain reaction (PCR) techniques have demonstrated HSV-2 latency in ganglia throughout the central nervous system (CNS) axis, albeit at significantly lower frequencies than in the sacral ganglia. Latency of HSV-2 has also been demonstrated to occur in trigeminal ganglia. The widespread latency of HSV-2 suggests that the virus may reach ganglia far removed from the site of primary infection." https://jamanetwork.com/journals/jamaneurology/fullarticle/795486

"Herpes simplex virus (HSV) DNA was detected in 42% of all [cranial] ganglia surveyed" https://pubmed.ncbi.nlm.nih.gov/11718247

"The presence of HSV-1 and VZV genomes in both sensory and autonomic ganglia suggests that latency (and perhaps, reactivation) of these viruses extends beyond the trigeminal ganglion. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782560/

"HSV - 2 can spread not only to the dorsal root sensory ganglia (DRG), but to the autonomic parasympathetic neurons of the major pelvic ganglia (MPG) and the sympathetic chain" https://jvi.asm.org/content/jvi/early/2019/02/22/JVI.00227-19.full.pdf

Thankyou, some very useful links there which at least confirm that cases like mine are not unknown as some would appear to want to suggest. 

 

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Elephant in the room?
43 minutes ago, Neuro_loss said:

Okay.....

Thanks, but any hint where this article might be found?

 

Try google T cells gut flora encephalitis. Can try to find it if u can’t. 

I know Wilso could crack it but it common knowledge and educated on in groups by well respected HSV advocates from organisations that the virus can travel via other nerve routes. Whether this has any baring or truth in your case at all no idea. 

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