Problem with animal models is they can show great results and then fail in humans and visa versa, thus never judge the work just yet before it's tested in humans and under the right circumstances. In this regard their attempt at targeting the genes during latency didn't go over so well, whereas it must be open more during replication like CRISPR. In this animal model it does not replicate, hence they will either try to repeat this in a guinea pig or try a different target.
It's not just Jerome, he's in charge but Martine Aubert did most of the grunt work.
While I did have an IgM test, which came out negative (and I know is complete bullshit), I also had an IgG test with differentiation between HSV-1 and HSV-2. I only tested positive for the HSV-2 antibodies, with a response of 15.5, which is pretty conclusively positive. I still don't know if I have genital or oral HSV-2, which is concerning, but I'm going to go on antivirals this week as a form of suppressive therapy. And my boyfriend was totally fine with my diagnosis! My ex was, too. Everyone I've told has been so supportive, which has really helped. I think, though, that the reason that they have been so supportive and accepting is because of how confident I was in my ability to not let this disease control me, and most of that confidence I received from here and from various articles I've read online trying to correct the social stigma and misinformation about this relatively harmless disease. I really want to help with outreach to the community now. Does anyone know of any charities or volunteer efforts going on in the metro NYC area that I could join or help out with?
Hi, I have recently found out I have type 2 herpes. I am in love with my partner, we have been together nearly a year...I have no idea how or when I contracted. I do not know how to tell him I have herpes because I seen his reaction to finding out a mutual friend had herpes and he was disgusted. Im so confused and afraid of losing him.
I had just a tiny bit of irritation in my woman parts. Kind of like the very beginning of a yeast infection. Then it went completely away and then it came back a few days later. During that time I had body aches and swollen lymph glands. One day I felt irritation from the lace in my underwear and went to the bathroom and saw like raised bumps. I put a cool washcloth and within a short time completely gone. It has been 2 and 1/2 weeks and no blisters. I feel completely fine lymph nodes back to normal. Tested negative to every single std including UTI and bacterial infection but to my horror positive to hsv2. Have you ever heard of something like this? I am so incredibly sad.
I was attacked, raped and stabbed 5 years ago and I finally felt I was getting my life together after suffering from severe PTSD. I feel like my world is slipping away once again. My guy helped me back into the world once more, but I don't know if we can survive this. He deserves better. I am afraid of taking daily suppression because after being stabbed I had to have most of my stomach removed due to infection. I am afraid of damaging what's left.
Sorry to unburden myself, but I feel so overwhelmed and ashamed.
If Cullen doesn't succeed then it's all about Halford. But we can't underestimate Cullen, he is going to push research to a whole different level imho.
Also Halford has been pretty optimistic of his trials going on. So if we are lucky may not even need Crispr.
Usually it will be something associated with why you got sunburnt. Holiday?
But generally yes, your body does a great job of suppressing it, especially if you have had the virus for years. Transmission rates can be very low, just a few percent chance per annum to a male.
What did your outbreak consist of and exactly where was it?